Betting on American Football is a unique endeavor. While it shares the same physical nature as rugby, football is a sport that requires its players to possess a high level of technical skill and a greater degree of precision than is normally required of players in other sports. Ghanaians count themselves among the ranks of this newfound fandom. They have been watching NFL playoff games and the Super Bowl itself into the wee hours of the morning. This is one of the reasons why we felt the need to put together an online football betting guide.

American football may not be Ghana's most traditional sport, but its betting markets are expanding rapidly, especially around the NFL and major college games. As a betting analyst who has reviewed platforms across Africa, I've created this 2025 guide to highlight the safest and most rewarding sites for American football betting. Each sportsbook featured here has been carefully vetted for payout speed, odds quality, and regulatory compliance - so you can bet with confidence and focus on the game.

Licensed Sportsbooks for American Football Betting in Ghana

Operator
Bonus
Features
Claim Now
300% Match

Bonus Up To GHS 3,445

✔ Daily Promotions

✔ FREE Bets
50% Match

Bonus Up To GHS 200

✔ Daily Promotions

✔ FREE Bets
200% Match

Bonus Up To GHS 3,100

✔ Daily Promotions

✔ FREE Bets
100% Match

Bonus Up To GHS 1,000

✔ Daily Promotions

✔ FREE Bets
400% Acca Win Boost

Bonus Up To GHS 100,000

✔ Daily Promotions

✔ FREE Bets
200% Slot Bonus

50% Cashback on Aviator

✔ Daily Promotions

✔ FREE Bets
100% Match

Bonus Up To GHS 3,000

✔ Daily Promotions

✔ FREE Bets
Daily Jackpot

Up To GHS 1,000,000

✔ Daily Promotions

✔ FREE Bets
100% Match

Bonus Up To GHS 2,000

✔ Daily Promotions

✔ FREE Bets

Top 5 American Football Betting Sites in Ghana 2025

Finding good American Football betting sites in Ghana requires careful consideration of several factors. I have looked at many platforms to show you the most reliable options for NFL betting in 2025. Each site offers Ghanaian bettors different advantages when betting on American football events.

1. Betway Ghana – Best for local support

Betway banner

Betway has become a top destination for American Football betting in Ghana since opening its Ghana office in 2016. The platform is distinguished by its detailed license from the Gaming Commission of Ghana (license numbers GCSB24K2300J and GCCA24A5339M). This ensures that you can bet safely.

The site has extensive NFL coverage with competitive odds and many betting markets. Their dedicated mobile apps for Android and iOS devices allow you to place NFL bets wherever you are. Ghanaian punters will appreciate that Betway processes all transactions in GHS, so there's no need to worry about currency conversion.

2. 1xBet – Best for odds variety

1xBet banner

1xBet excels in offering different betting markets for American Football fans. The platform supports over 100 verified payment methods with low withdrawal fees. This makes it very convenient for Ghanaian bettors.

1xBet's impressive selection of NFL markets sets it apart. You'll find everything from point spreads to parlays and over/under totals. New users receive a welcome bonus of up to GHS 2,650, giving them a great chance to try out different NFL betting options.

Their sportsbook app comes with all website features, so you get uninterrupted mobile betting on NFL games.

3. Paripesa – Best for mobile betting

Paripesa banner

Paripesa's mobile app is known for its easy-to-use design, specifically designed for smartphones and tablets. The app has several innovative features that make NFL betting better.

The Cash Out option allows you to settle your bets before the events end. This gives you more control over potential profits or losses based on live scores. This feature is especially helpful during unpredictable NFL games.

Paripesa also has unique features such as bet insurance, which protects bets against unexpected outcomes, and an edit bet feature, which allows you to adjust selections and potential payouts before finalizing. Their payment system works with popular Ghanaian methods like MTN, AirtelTigo and Vodafone Cash.

4. 22Bet – Best for bonuses

22Bet banner

22Bet offers new users an impressive 200% welcome bonus up to 1,000 GHS. This makes it really attractive to start your NFL betting experience. All you have to do is enter the Promo code 22BTGO when you register.

The bonus has reasonable wagering requirements - 7x on accumulator bets with at least two selections and minimum odds of 3.00. Active players can easily meet these requirements within the 7 day window.

22Bet also has ongoing promotions such as the Friday Reload Bonus (50% up to 1,200 GHS) and Risk Free Bets up to 650 GHS. These offers will enhance your NFL betting experience throughout the season.

5. Melbet – Best for live betting

Melbet banner

Melbet does a great job with live betting options on NFL games. Their platform allows you to bet in real time on over 200 events a day in all kinds of sports. This makes it perfect for in-game NFL betting.

Odds update instantly as the game progresses, allowing you to take advantage of momentum shifts during NFL games. Melbet also offers helpful real-time stats and game watchers to help you make smart decisions during live NFL games.

Ghanaian bettors who love American Football will appreciate Melbet's competitive odds and easy-to-use interface that makes following and betting on the NFL action easy and fun.

How to Choose the Best American Football Betting Site

Best Sites banner

Choosing the right platform to bet on American Football in Ghana requires you to look at several key factors. I've spent years placing NFL bets and want to share my step-by-step approach to finding good betting sites.

Check for a valid Ghana Gaming Commission license

The first step is to make sure that any American football betting site is operating legally in Ghana. The Gaming Commission of Ghana issues sports betting licenses and keeps an eye on the gaming industry. Foreign sites can operate legally in Ghana if they meet two requirements:

  • Ghanaians must own part of the business (this is why companies like Parimatch and 1xBet work with local partners)
  • they must have At least one physical office in Ghana (most international bookmakers set up in Accra);

Stay away from unlicensed operators - the Gaming Commission warns people "not to deal with any unlicensed gambling company".

Compare odds and betting markets

Once you know a site is legal, take a look at their odds. You'll see that different NFL betting sites show different odds for similar games and markets. This happens because some online sportsbooks take a larger cut, or "vig," which means less money for you.

The best American Football betting sites in Ghana give you plenty of options - from basic game lines to Player props and NFL futures. More betting choices means a better chance of finding good bets.

Look for NFL and college football coverage

NFL betting is standard everywhere, but the best sites will also let you bet on college football. American football isn't big worldwide, so if a bookmaker covers both pro and college games, it shows they're serious about the sport.

Review user experience and mobile app quality

Ghanaian punters need good mobile betting options. Sites with quality apps or mobile-friendly websites allow you to place bets wherever you are. Look for platforms with data-efficient apps - some have lite versions as small as 2.8MB that use minimal internet data.

Key features to watch for:

  • Live betting and streaming capabilities
  • Cash out options
  • Bet builder functionality
  • Competitive odds;

Read reviews and user feedback

Real user experiences are a great way to gain insight. I always check independent reviews and what other users are saying before choosing a platform. This helps to identify any issues with payments, customer service or odds that may not be obvious at first.

Your betting style should guide your choice. Someone who bets on the Super Bowl needs different features than someone who bets live during the regular season. Don't just go with the most popular site - find one that suits the way you want to bet on American football in Ghana.

Bonuses and Promotions to Look Out For

Bonuses and Promotions banner

Attractive bonuses at the time of choosing American Football betting sites in Ghana can give your bankroll and betting opportunities a big boost. I've tested several platforms and found the most valuable promotions for NFL bettors.

Welcome bonuses for new users

The top American Football betting platforms in Ghana are offering impressive welcome packages to first time bettors. 1xBet leads the pack with a welcome bonus of up to 300%, which can reach GHS 2,650. The bonus works in tiers:

  • A 200% match for deposits up to 380 GHS
  • A 250% match for deposits between 381-760 GHS
  • The maximum 300% bonus for deposits over 761 GHS;

Betway keeps things simple with a 50% up to GHS 200 welcome bonus. This bonus is easy to clear as you only need a Minimum deposit of GHS 1.

22Bet offers a higher value option with a 200% first deposit bonus up to GHS1,000 and you have 7 days to clear it. These offers work best if you check the wagering requirements first - they usually range from 5x to 8x the bonus amount.

Risk-free bets and cashback offers

Betboro's cashback offer of up to 400 GHS gives you a safety net for your first bets. If your first bet loses, you'll get your entire stake back in free bets. The deal gets even better - Winners get 50% of their stake back (up to 400 GHS).

Daily cashback promotions have become popular with punters. Most sites offer a 10% return on daily losses, with cashbacks starting at 10 GHS and going up to 1,000 GHS.

Super Bowl and NFL season promos

The Super Bowl brings out special promos on American Football betting platforms in Ghana. You'll find better odds, free bets and unique prop betting markets during this time.

The NFL regular season brings valuable accumulator boosts. Betika's 400% accumulator win boost can pay up to GHS 100,000. Your potential payout grows based on how many selections you add to your betting slip - perfect for multiple NFL game parlays.

Loyalty and VIP programs

Betway's new rewards program gives consistent NFL bettors ongoing value. Every sports bet earns points that can be converted directly into cash. The points are equal to the currency value (50 points = GHS 50) and appear instantly in your account.

Betway's system allows you to convert points into cash whenever you want. You can place more bets or withdraw the money without any restrictions. This flexibility comes in handy during the playoff season when betting picks up.

Other bookmakers offer tiered VIP programs with monthly rewards based on how much you bet. These come with personalized service, special promotions and extra perks like birthday bonuses for loyal customers.

Payment Methods Available on Ghana Betting Sites

Payment Methods Available on Ghana Betting Sites infographic

Easy deposits and withdrawals make a big difference in Ghana NFL betting. My tests of betting platforms show several reliable payment options that Ghanaian NFL bettors can use.

MTN Mobile Money

MTN Mobile Money dominates betting payments in Ghana with a 70% market share. The platform Processes transactions instantly, so you can place NFL bets instantly. All major Ghanaian NFL betting sites such as Betway, 1xBet and 22Bet support MTN MoMo. The service uses top-notch security protocols to keep your data safe during transactions.

Vodafone Cash

Vodafone Cash holds 20% of Ghana's mobile money market and serves as a reliable way to fund betting accounts. The service features low fees and a Secure two-factor authentication system. Punters can transact up to 60,000 EGP per day, which works well for both casual and serious NFL betting.

AirtelTigo Money

AirtelTigo Money has a 10% market share, but more NFL betting sites in Ghana are now accepting it. The service processes deposits as fast as other mobile money options at 1xBet and 22Bet. You can Deposit by dialing *500#, selecting 'buy goods', then 'other' and following the instructions.

Bank transfers and cards

Bank transfers work better for larger transactions with higher limits. Betway allows you to deposit up to GHS 1,000,000 using bank cards, while mobile money stops at GHS 100,000. These transfers use advanced fraud detection systems, but take 1-7 business days to process.

E-wallets and crypto options

Skrill and NETELLER e-wallets allow you to pay semi-anonymously and most sites accept them. Cryptocurrency has also become popular among Ghanaian NFL bettors. 22Bet accepts Bitcoin, Ethereum, Tether and Cardano with instant deposits and withdrawals.

Mobile Betting and App Experience

Mobile betting has changed the way Ghanaians bet on American football games. The ability to bet from anywhere makes a huge difference.

Which sites have the best apps?

1xBet leads American Football betting sites in Ghana with a detailed mobile experience and a feature-rich app for iOS and Android. Betway Ghana stands out for its beautiful design and smooth functionality. Betwinner keeps things simple with an accessible interface that displays all tabs right on the homepage. Parimatch stands out for its fast response times.

Mobile-exclusive bonuses

American Football betting platforms in Ghana give special rewards to mobile users. Mobile users get free bets and better odds that desktop users can't access. These exclusive offers help convince punters to download and use the apps.

Live betting on mobile

Mobile platforms have fast loading times for live betting. Apps like 1xBet's have stats sections that enhance your in-game betting choices. Push notifications help you keep track of game progress, odds updates and betting opportunities.

Data-saving features for Ghana users

Odibets' ultra-light app weighs only 2.8MB. This app uses minimal data while keeping all features working. These optimized apps make American Football betting in Ghana work smoothly even on slower networks.

Final Verdict

Verdict banner

Each platform brings something special to the table. Betway Ghana excels in local support, while 1xBet gives you a great variety of odds. Paripesa makes mobile betting easy, 22Bet offers amazing bonuses, and Melbet really shines with live betting. Your best choice will depend on what is most important to you.

Choosing a safe American football betting site should be your first priority. Make sure the platform is Licensed by the Gaming Commission of Ghana before you sign up. Take the time to look at the odds on different sites, check out the NFL markets, and test how well they work on your phone to get the most out of your bets.

Bonuses can make your betting experience better. 1xBet leads the way with a 300% welcome bonus up to GHS 2,650. Risk-free bets and cashback offers help protect your wagers, and loyalty programs reward you for betting regularly.

Pick the right platform, bet wisely, and here's hoping your NFL predictions pay off this season!